Nugenix known for promising increased energy, enhanced muscle mass, and improved libido. But does it deliver?
With a blend of well-known ingredients like Tesnor®, D-Aspartic Acid, Boron, and Zinc, Nugenix markets itself as a research-backed supplement for men experiencing age-related testosterone decline.
We’ve taken a deep dive into its ingredients, effectiveness, potential drawbacks, and real-world user experiences to help you decide whether it’s the right choice for you.
Nugenix offers multiple formulations, including Nugenix Total-T, Nugenix Ultimate, and Nugenix Free Testosterone Booster, each with varying ingredient compositions. However, several core ingredients are found across these products:
Tesnor® (Pomegranate + Cocoa Extract): A patented blend with some promising research. A 2024 study found that 400mg daily over 12 weeks increased free testosterone by 25% and total testosterone by 18%. It also showed mild improvements in strength and energy.
D-Aspartic Acid (DAA): Included in Nugenix Ultimate, this amino acid has mixed results. A 2024 trial showed a 10-15% testosterone increase in 40% of users, but no effect in the remaining 60%.
Zinc (1mg in Total-T, 10mg in Ultimate): An essential mineral for testosterone production. However, clinical studies suggest doses below 5mg have little effect, making the low dosage in some Nugenix products questionable.
Boron (10mg in Ultimate): A solid addition, as research indicates it can lower sex hormone-binding globulin (SHBG) by 20-30%, effectively increasing free testosterone levels.
L-Citrulline Malate: Included for its role in improving blood flow, though it does not directly impact testosterone.
Tribulus Terrestris: Traditionally used to enhance libido, but research shows it doesn’t significantly impact testosterone in humans.
One of the biggest concerns is the under-dosing of key ingredients. While Tesnor® and Boron are well-dosed, Zinc and D-Aspartic Acid are below the clinically effective range in certain formulations. This means that while some benefits may be noticeable, others might be too minimal to make a significant difference.
The effectiveness of Nugenix depends on several factors, including your baseline testosterone levels, diet, exercise routine, and individual response to supplementation. Here’s what we found:
Men with low or borderline-low testosterone levels (≤300 ng/dL) reported the most noticeable improvements, particularly in energy and mental clarity.
Tesnor®’s effects on free testosterone appear legitimate, supported by research showing improvements in strength and well-being.
Boron’s ability to lower SHBG means that even if total testosterone levels don’t change significantly, free testosterone (the usable form) may increase.
If you already have normal testosterone levels, Nugenix may have little noticeable effect.
Zinc’s dosage is too low to make a real impact unless you’re deficient.
DAA’s response rate is inconsistent, with only 40% of users in studies experiencing a testosterone increase.
Tribulus is largely ineffective for testosterone increases, though some men report improved libido.
Nugenix is generally well-tolerated, but some users report:
Stomach discomfort (likely due to L-Citrulline Malate)
Gastrointestinal issues
Headaches or mild nausea
Splitting doses or taking Nugenix with food may help mitigate these side effects.
Another concern is the cost-to-benefit ratio. At $0.72 per serving, it is priced as a premium supplement, yet some competitors offer higher-dosed formulations for less.
Consumer sentiment around Nugenix is polarizing:
40% of Amazon and CVS reviews rate it 4-5 stars, citing increased energy, motivation, and slight strength gains.
35% of reviews rate it 1-2 stars, with complaints of no measurable testosterone increase and issues with pill size.
25% of users report only subtle effects, often linking results to exercise and diet improvements rather than the supplement itself.
A 2025 Consumer Reports survey found that only 30% of testosterone booster users reported sustained benefits after 3 months, suggesting either diminishing returns or a placebo effect.
Men with low-to-moderate testosterone levels (≤300-450 ng/dL)
Those looking for a mild testosterone boost without synthetic hormones
Individuals who combine supplementation with diet and exercise
Men with already normal testosterone levels
Those seeking a higher-dose, more cost-effective alternative
Anyone expecting dramatic strength and muscle gains solely from a supplement
Nugenix offers some evidence-backed ingredients, particularly Tesnor® and Boron, but its effectiveness depends on individual factors. The low Zinc and inconsistent DAA response make its impact uncertain for some users.
If you’re willing to invest and pair it with lifestyle changes, Nugenix could be a useful addition. But for those seeking the strongest, most cost-effective testosterone boost, other options with better-dosed ingredients might be a better fit.
As always, consult a healthcare provider before starting any supplement, especially if you have underlying health conditions.